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dc.contributor.authorDuarte, Marvery Peterson-
dc.contributor.authorNóbrega, Otávio de Tolêdo-
dc.contributor.authorVogt, Barbara P.-
dc.contributor.authorPereira, Marina S.-
dc.contributor.authorVieira, Fábio A.-
dc.contributor.authorSilva, Maryanne Z. C.-
dc.contributor.authorDisessa, Henrique S.-
dc.contributor.authorMondini, Dario R.-
dc.contributor.authorKrug, Rodrigo R.-
dc.contributor.authorSant’Helena, Bruna M.-
dc.contributor.authorBundchen, Daiana C.-
dc.contributor.authorBohlke, Maristela-
dc.contributor.authorAdamoli, Angélica N.-
dc.contributor.authorLima, Ricardo M.-
dc.contributor.authorInda-Filho, Antônio J.-
dc.contributor.authorAvesani, Carla M.-
dc.contributor.authorReboredo, Maycon M.-
dc.contributor.authorRibeiro, Heitor S.-
dc.contributor.authorThe SARC-HD Study Group-
dc.date.accessioned2026-10-14T12:34:32Z-
dc.date.available2026-10-14T12:34:32Z-
dc.date.issued2026-01-05-
dc.identifier.citationDUARTE, Marvery P. et al. Prevalence of and factors associated with sarcopenia in patients on hemodialysis in Brazil: findings from the multicenter sarc-hd study. Frontiers in Medicine, [S. l.], v. 12, 1671237, 2026. DOI: https://doi.org/10.3389/fmed.2025.1671237. Disponível em: https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2025.1671237/full. Acesso em: 14 out. 2026.pt_BR
dc.identifier.urihttp://repositorio.unb.br/handle/10482/57227-
dc.language.isoengpt_BR
dc.publisherFrontiers Media SApt_BR
dc.rightsAcesso Abertopt_BR
dc.titlePrevalence of and factors associated with sarcopenia in patients on hemodialysis in Brazil : findings from the multicenter sarc-hd studypt_BR
dc.typeArtigopt_BR
dc.subject.keywordSarcopeniapt_BR
dc.subject.keywordForça muscularpt_BR
dc.subject.keywordCircunferência da panturrilhapt_BR
dc.subject.keywordDoença renal crônicapt_BR
dc.subject.keywordHemodiálisept_BR
dc.subject.keywordEpidemiologiapt_BR
dc.rights.licenseThis is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.pt_BR
dc.identifier.doihttps://doi.org/10.3389/fmed.2025.1671237pt_BR
dc.description.abstract1Objective The understanding of sarcopenia in patients on hemodialysis from middle-income countries remains underexplored. We investigated the prevalence of and factors associated with sarcopenia in patients undergoing hemodialysis in Brazil. Methods This was a cross-sectional analysis using baseline data from the SARC openia trajectories and associations with clinical outcomes in patients on Hemo Dialysis (SARC-HD) multicenter study. Muscle strength was assessed by handgrip, muscle mass by calf circumference, and physical performance by the 4-m gait speed test. Sarcopenia was diagnosed and staged as probable, confirmed, or severe based on the revised European Working Group on Sarcopenia in Older People (EWGSOP2) consensus. Associated factors were investigated with adjustment for potential confounders. Results A total of 983 patients (median age 59 years; 48% ≥ 60 years; 40% female) from 19 dialysis centers were analyzed. The prevalences of probable, confirmed, and severe sarcopenia were 12, 9, and 5%, respectively. Sarcopenia prevalence increased with age, ranging from 7 to 45% in the male individuals and from 4 to 21% in the female individuals. In the fully adjusted model, older age [≥60 years; adjusted odds ratio (aOR): 3.30, 95% confidence interval (CI): 2.09–5.21], male sex (aOR: 1.77, 95% CI: 1.13–2.77), white ethnicity (aOR: 1.88, 95% CI: 1.23–2.87), and diabetes as the etiology/comorbidity of chronic kidney disease (CKD) (aOR: 1.83, 95% CI: 1.20–2.91) were independently associated with higher odds of sarcopenia. Nevertheless, overweight (aOR: 0.38, 95% CI: 0.24–0.60) and obesity (aOR: 0.11, 95% CI: 0.05–0.26) were associated with lower odds. After sensitivity analyses based on dialysis prescription, only older age, white ethnicity, overweight, and obesity remained independently associated with sarcopenia. Conclusion One in four patients on hemodialysis had some stage of sarcopenia. Independent risk factors associated with sarcopenia were older age and white ethnicity, whereas overweight and obesity were protective factors. These findings may help identify hemodialysis patients at increased risk of sarcopenia, thereby promoting early screening, diagnosis, and treatment strategies.en
dc.contributor.affiliationUniversity of Brasilia, Faculty of Health Sciencespt_BR
dc.contributor.affiliationUniversity of Brasilia, Faculty of Health Sciencespt_BR
dc.contributor.affiliationFederal University of Uberlandia, Medicine Facultypt_BR
dc.contributor.affiliationFederal University of Juiz de Fora, School of Medicinept_BR
dc.contributor.affiliationUniversity of Brasilia, Faculty of Health Sciencespt_BR
dc.contributor.affiliationSão Paulo State University, Department of Physical Education, Baurupt_BR
dc.contributor.affiliationState University of Campinas, Faculty of Physical Education, Laboratory of Applied Kinesiologypt_BR
dc.contributor.affiliationUniversity of Cruz Alta, Postgraduation Program in Comprehensive Health Carept_BR
dc.contributor.affiliationIELUSC Faculty, Joinville, Brazilpt_BR
dc.contributor.affiliationFederal University of Santa Catarina, Department of Health Sciences, Araranguá, Brazilpt_BR
dc.contributor.affiliationCatholic University of Pelotas, Postgraduate Program in Health and Behaviorpt_BR
dc.contributor.affiliationHospital de Clínicas de Porto Alegrept_BR
dc.contributor.affiliationUniversity of Brasilia, Faculty of Physical Educationpt_BR
dc.contributor.affiliationUniversity of Brasilia, Faculty of Health Sciencespt_BR
dc.contributor.affiliationDepartment of Clinical Science, Technology and Intervention, Division of Renal Medicine and Baxter Novum, Karolinska Institute, Stockholm, Swedenpt_BR
dc.contributor.affiliationUniversity of Brasilia, Faculty of Health Sciencespt_BR
dc.description.unidadeFaculdade de Ciências da Saúde (FS)pt_BR
dc.description.unidadeFaculdade de Ciências e Tecnologias em Saúde (FCTS) – Campus UnB Ceilândiapt_BR
dc.description.ppgPrograma de Pós-Graduação em Ciências da Saúdept_BR
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