Title:	Enhancing life with celiac disease : unveiling effective tools for assessing health-related quality of life
Authors:	Falcomer, Ana Luísa Lima, Bernardo Romão de Gouveia, Priscila Farage de Fabbris, Samanta Nascimento Ritter, Ruth Helena Raposo, António Lemos, Edite Teixeira de Chaves, Cláudia Balula Magalhaes, Renata Puppin Zandonadi
metadata.dc.identifier.orcid:	https://orcid.org/0000-0003-2361-8906 https://orcid.org/0000-0001-5257-2586 https://orcid.org/0000-0002-5286-2249 https://orcid.org/0000-0002-4030-0863 https://orcid.org/0009-0001-4062-7102 https://orcid.org/0000-0003-0370-3089
metadata.dc.contributor.affiliation:	University of Brasília, Faculty of Health Sciences, Department of Nutrition Centro Universitário IESB, Department of Nutrition University of Brasília, Faculty of Health Sciences, Department of Nutrition Centro Universitário IESB, Department of Nutrition Federal University of Goiás, Faculty of Nutrition (FANUT) University of Brasília, Faculty of Health Sciences, Department of Nutrition University of Brasília, Faculty of Health Sciences, Department of Nutrition Universidade Lusófona de Humanidades e Tecnologias, CBIOS (Research Center for Biosciences and Health Technologies) Polytechnic University of Viseu, CERNAS Research Centre Polytechnic University of Viseu, Centre for Studies in Education and Innovation (CI&DEI), ESSV University of Brasília, Faculty of Health Sciences, Department of Nutrition
Assunto::	Doença celíaca Qualidade de vida relacionada à saúde Dieta sem glúten Revisão sistemática
Issue Date:	29-Apr-2024
Publisher:	Frontiers
Citation:	FALCOMER, Ana Luísa et al. Enhancing life with celiac disease: unveiling effective tools for assessing health-related quality of life. Frontiers in Immunology, [S.l.], v. 15, e1396589, 2024. DOI: https://doi.org/10.3389/fimmu.2024.1396589. Disponível em: https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2024.1396589/full. Acesso em: 12 fev. 2026.
Abstract:	Celiac disease (CD) is an autoimmune chronic enteropathy provoked by gluten ingestion in genetically predisposed individuals. Considering it´s only safe treatment is a lifelong gluten-free diet, the burden of living with the disease becomes evident, as well as the need to assess CD health-related quality of life (HRQOL). This review aims to identify and analyze the instruments used to evaluate the HRQOL of adults with CD. This integrative review using a systematic approach was designed to achieve high scientific standards. Accordingly, the search strategy was developed and executed as recommended by the guideline of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. Detailed individual searches were developed to Pubmed, Science Direct, Scopus, Web of Science, and Google Scholar. After careful analysis of the papers, 43 studies were included, in which seven instruments were identified: Celiac Disease Questionnaire (CDQ) (n=21), Celiac Disease Specific Quality of Life Instrument (CD-QOL) (n=17), Celiac Disease Assessment Questionnaire (CDAQ) (n=4), CeliacQ-7 (n=1), CeliacQ-27 (n=1), Black and Orfila´s self-developed instrument (n=1) and the Coeliac Disease Quality of Life Questionnaire (CDQL) (n=1). The CDQ and CD-QOL were the two most applied instruments. Since the first focuses on the physical and mental symptoms related to the disease and the second focuses on the emotional repercussions of adhering to the GFD treatment for life (dysphoria), the CDQ application is an interesting option for countries that struggle with public policies for CD patients and patients with active CD. The CD-QOL could be used for countries with strict regulations for CD and gluten-free products and populations in remission. When comparing results among different populations, it is preferable to utilize culturally validated instruments, which have been applied across multiple countries, providing greater comparability between study findings.
metadata.dc.description.unidade:	Faculdade de Ciências da Saúde (FS) Departamento de Nutrição (FS NUT)
metadata.dc.description.ppg:	Programa de Pós-Graduação em Nutrição Humana
Licença::	This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
DOI:	https://doi.org/10.3389/fimmu.2024.1396589
Appears in Collections:	Artigos publicados em periódicos e afins

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