Titre:	Anemia materna e peso ao nascer
Auteur(s):	Figueiredo, Ana Claudia Morais Godoy
Orientador(es)::	Pereira, Maurício Gomes
Assunto::	Anemia Mulheres grávidas Gestantes Baixo peso ao nascer (BPN) Recém-nascidos - peso baixo
Date de publication:	12-déc-2018
Data de defesa::	23-fév-2018
Référence bibliographique:	FIGUEIREDO, Ana Claudia Morais Godoy. Anemia materna e peso ao nascer. 2018. 150 f., il. Tese (Doutorado em Saúde Coletiva) — Universidade de Brasília, Brasília, 2018.
Abstract:	Anemia is a common condition amongst pregnant women due to physiological alterations caused by pregnancy. It is possible that still unknown causal factors contribute to the high incidence of anemia during pregnancy. Furthermore, anemia might be responsible for undesirable outcomes such as low birth weight, prematurity, and maternal-infant mortality. OBJECTIVE: To verify the association between maternal anemia and birth weight. METHOD: It consisted of two parts. In the first, a systematic review was conducted with cohort and case-control studies on maternal anemia and low birth weight. Indexed articles, which met the eligibility criteria in the main databases of the health literature were selected. The descriptors used in the search strategies were: anemia, pregnant women, low birth weight, case-control studies and cohort. There was no limitation on language or date of publication. Meta-analyzes, sensitivity, subgroups analyzes, meta-regressions and verification of the existence of publication bias were performed. The second part comprised a cohort study developed with pregnant women who underwent prenatal follow-up at Family Health Units in the city of Santo Antônio de Jesus, Bahia. The pregnant women answered a questionnaire through an interview to obtain socioeconomic-demographic information, related to lifestyle and reproductive history. They were classified according to the diagnosis of maternal anemia, hemoglobin value less than 11 g / dl, according to the criteria of the World Health Organization. After delivery, these women were grouped according to the low / insufficient birth weight of the newborns, less than 2,999 g. Robust Poisson regression analysis was performed to obtain the association measurement between maternal anemia and low / insufficient birth weight, relative risk and confidence interval, considering effect modifiers and confounders. RESULTS: are presented in the form of three articles. 1) Conceptual article entitled: "Maternal anemia and iron deficiency anemia: their similarities and singularities", originated from the review of studies on the theme that addressed aspects related to both the diagnosis, treatment and prevention process of anemia during pregnancy in relation to the policy to combat maternal anemia. 2) A systematic review paper that evaluated 71 studies and concluded, through meta-analysis, that maternal anemia is a strong risk factor for low birth weight. 3) Article entitled "maternal anemia and low birth weight: a prospective cohort study" conducted with 622 pregnant women and their newborns followed up until delivery. The results showed that mothers with maternal anemia are at higher risk of having children with low / insufficient birth weight than those without anemia. CONCLUSIONS: The findings obtained in this thesis indicate that maternal anemia is a frequent event in the investigated population, of moderate occurrence, as well as being an important risk factor for low / insufficient birth weight. It may produce irreversible impacts to the maternal-infant binomial, which suggests the need for prevention and control measures.
metadata.dc.description.unidade:	Faculdade de Ciências da Saúde (FS)
Description:	Tese (doutorado) — Universidade de Brasília, Faculdade de Ciências da Saúde, Programa de Pós-Graduação em Saúde Coletiva, 2018.
metadata.dc.description.ppg:	Programa de Pós-Graduação em Saúde Coletiva
Agência financiadora:	Fundação de Amparo à Pesquisa do Estado da Bahia (FAPESB), Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) e Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES).
Collection(s) :	Teses, dissertações e produtos pós-doutorado

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