| Campo DC | Valor | Idioma |
| dc.contributor.author | Kubota, Aline Midori Adati | - |
| dc.contributor.author | Rosa, Mário Fabrício Fleury | - |
| dc.contributor.author | Baraldi, Solange | - |
| dc.contributor.author | Vale, Janine Araújo Montefusco | - |
| dc.contributor.author | Silva, Joana D`arc Gonçalves da | - |
| dc.contributor.author | Carneiro, Marcella Lemos Brettas | - |
| dc.contributor.author | Padula, Rosimeire Simprini | - |
| dc.contributor.author | Haddad, Rodrigo | - |
| dc.contributor.author | Joanitti, Graziella Anselmo | - |
| dc.contributor.author | Luz, Glécia Virgolino da Silva | - |
| dc.contributor.author | Fook, Marcus Vinícius Lia | - |
| dc.contributor.author | Zimmermann, Ivan Ricardo | - |
| dc.contributor.author | Rosa, Suélia de Siqueira Rodrigues Fleury | - |
| dc.contributor.author | Peixoto, Henry Maia | - |
| dc.contributor.author | Carregaro, Rodrigo Luiz | - |
| dc.date.accessioned | 2026-09-18T11:17:55Z | - |
| dc.date.available | 2026-09-18T11:17:55Z | - |
| dc.date.issued | 2024-09-27 | - |
| dc.identifier.citation | KUBOTA, Aline Midori Adati et al. Efficacy and feasibility of a novel semi-facial respirator with chitosan nanoparticles on the incidence of SARS-CoV-2 infection in healthcare professionals: randomized controlled trial. BMC Infectious Diseases, [S. l.], v. 24, n. 1061, 2024. DOI; https://doi.org/10.1186/s12879-024-09966-x. Disponível em: https://link.springer.com/article/10.1186/s12879-024-09966-x. Acesso em: 18 set. 2026. | pt_BR |
| dc.identifier.uri | http://repositorio.unb.br/handle/10482/55931 | - |
| dc.language.iso | por | pt_BR |
| dc.publisher | BMC | pt_BR |
| dc.rights | Acesso Aberto | pt_BR |
| dc.title | Efficacy and feasibility of a novel semifacial respirator with chitosan nanoparticles on the incidence of SARS-CoV-2 infection in healthcare professionals : randomized controlled trial | pt_BR |
| dc.type | Artigo | pt_BR |
| dc.subject.keyword | SARS-CoV-2 | pt_BR |
| dc.subject.keyword | Covid-19 | pt_BR |
| dc.subject.keyword | Saúde ocupacional | pt_BR |
| dc.rights.license | Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http:// creativecommons.org/licenses/by-nc-nd/4.0/. | pt_BR |
| dc.identifier.doi | https://doi.org/10.1186/s12879-024-09966-x | pt_BR |
| dc.description.abstract1 | Background Evidence suggests that semi-facial respirators provide protection against contamination in high-risk
environments, although the COVID-19 pandemic called for greater protection and viral inactivation capacity. Thus, the
aim of this study was to investigate the efficacy of a novel semi-facial respirator containing chitosan nanoparticles,
compared with a conventional N95 respirator on the incidence of laboratory-confirmed SARS-CoV-2 in healthcare
professionals. The secondary outcomes were influenza infection, usability and comfort.
Methods Randomized controlled trial within a large public hospital (reference for COVID-19 patients) carried out
between March 2021 and June 2023. We included 230 healthcare professionals exposed to SARS-Cov-2 and influenza,
working in emergency departments, hospital wards, and intensive care units. Participants were assessed at baseline,
after 10 days, and 21 days of follow-up. Researchers, participants, and outcome assessors were blinded to the
allocated groups. Outcomes were analyzed by bivariate and multivariate comparisons using logistic regression. Crude
(cOR) and adjusted odds ratios (aOR) were estimated, followed by 95% confidence intervals (CIs 95%). We adopted
intention-to-treat (ITT) and complete-case (CC) analyses.
Results Baseline characteristics were considered homogeneous between groups, and usability and comfort were
reported as excellent in both groups. Non-significant differences were found for all outcomes, both in the ITT and
CC analyses. The incidence of COVID-19 and influenza were, respectively, cOR: 0.96 [CI95%: 0.21–4.42] and cOR: 1.25
[CI95%: 0.34–4.62]; and aOR: 1.08 [CI95%: 0.21–5.47] and aOR: 1.11 [CI95%: 0.17–7.01]. Conclusions We found that the incidence of SARS-Cov-2 and influenza infections were similar between the new
respirator compared to the conventional respirator. Furthermore, we observed that usability and comfort were similar
and considered excellent for both respirators. | pt_BR |
| dc.description.unidade | Faculdade de Ciências e Tecnologias em Saúde (FCTS) – Campus UnB Ceilândia | pt_BR |
| dc.description.unidade | Curso de Fisioterapia (FCTS-FISIO) | pt_BR |
| dc.description.ppg | Programa de Pós-Graduação em Ciências da Reabilitação | pt_BR |
| Aparece nas coleções: | Artigos publicados em periódicos e afins
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