A greener approach for the synthesis of pyrido[2,3-d]pyrimidine derivatives in glycerol under microwave heating

Martinho, Luan Alves; Andrade, Carlos Kleber Zago de

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Campo DC	Valor	Lengua/Idioma
dc.contributor.author	Martinho, Luan Alves	pt_BR
dc.contributor.author	Andrade, Carlos Kleber Zago de	pt_BR
dc.date.accessioned	2026-08-16T18:50:55Z	-
dc.date.available	2026-08-16T18:50:55Z	-
dc.date.issued	2022-8	pt_BR
dc.identifier.citation	MARTINHO, Luan Alves. ANDRADE, Carlos Kleber Zago. A greener approach for the synthesis of pyrido[2,3-d]pyrimidine derivatives in glycerol under microwave heating. Journal of Heterocyclic Chemistry, [S. l.], v. 59, n. 8, p. 1417-1429, 2022. DOI: https://doi.org/10.1002/jhet.4483. Disponível em: https://onlinelibrary.wiley.com/doi/epdf/10.1002/jhet.4483. Acesso em: 16 ago. 2026.	pt_BR
dc.identifier.uri	https://doi.org/10.1002/jhet.4483	pt_BR
dc.identifier.uri	http://repositorio.unb.br/handle/10482/55675	-
dc.description.sponsorship	Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Universidade de Brasília, Grant/Award Number: Edital004/2021DPG	-
dc.publisher	Wiley	pt_BR
dc.rights	Acesso Restrito	pt_BR
dc.title	A greener approach for the synthesis of pyrido[2,3-d]pyrimidine derivatives in glycerol under microwave heating	pt_BR
dc.type	Artigo	pt_BR
dc.subject.keyword	Solventes orgânicos	pt_BR
dc.subject.keyword	Pirido[2,3-d]pirimidinas	pt_BR
dc.identifier.doi	https://doi.org/10.1002/jhet.4483	pt_BR
dc.relation.publisherversion	https://onlinelibrary.wiley.com/doi/10.1002/jhet.4483	-
dc.description.abstract1	Herein, we report the multicomponent synthesis of pyrido[2,3‐d]pyrimidine derivatives from 6‐aminouracil, aromatic aldehydes, and malononitrile in glycerol as a green solvent under microwave heating. This methodology shows several advantages: catalyst‐free synthesis, up to 90% yield, operational simplicity, short reaction times, easy work‐up procedure, and a greener approach compared with other methods reported in the literature.	pt_BR
dc.abstract	Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Universidade de Brasília, Grant/Award Number: Edital004/2021DPG	pt_BR
dc.identifier.orcid	https://orcid.org/0000-0001-6658-5847	pt_BR
dc.identifier.orcid	https://orcid.org/0000-0003-0798-9133	pt_BR
dc.contributor.affiliation	Universidade de Brasília, Instituto de Química, Laboratório de Química Metodológica e Orgânica Sintética (LaQMOS)	pt_BR
dc.contributor.affiliation	Universidade de Brasília, Instituto de Química, Laboratório de Química Metodológica e Orgânica Sintética (LaQMOS)	pt_BR
dc.description.unidade	Instituto de Química (IQ)	pt_BR
dc.description.ppg	Programa de Pós-Graduação em Química	pt_BR
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