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dc.contributor.authorCoelho, Camila Pinho e Souza-
dc.contributor.authorSilva, Joana Rodrigues da-
dc.contributor.authorMarques, Rafaella Cristhina Rego-
dc.contributor.authorMelo, Jéssica Luiza Mendonça Albuquerque de-
dc.contributor.authorAlves, Larisse Mendonça-
dc.contributor.authorMelo, Carlos Daniel Correa de Oliveira-
dc.contributor.authorLeite, Eduarda Carvalho-
dc.contributor.authorFernandes, Priscilla-
dc.contributor.authorBrasil, Rafael Lara-
dc.contributor.authorPereira Neto, Pedro Chagas-
dc.contributor.authorNunes, Fernanda de Paula e Silva-
dc.contributor.authorBaraldi, Solange-
dc.contributor.authorHeller, Debora-
dc.contributor.authorGuimarães, Maria do Carmo Machado-
dc.contributor.authorLia, Érica Negrini-
dc.contributor.authorTeixeira, Nailê Dame-
dc.date.accessioned2026-02-24T19:07:30Z-
dc.date.available2026-02-24T19:07:30Z-
dc.date.issued2026-01-
dc.identifier.citationCOELHO, C. P. S. et al. Salivary flow and aging : a cross-sectional estimate of the annual decline per year of age. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, [S. l], v. 141, 1, 2026. Disponível em: https://www.sciencedirect.com/science/article/pii/S2212440325011642?via%3Dihub. Acesso em: 24 fev. 2026.pt_BR
dc.identifier.urihttp://repositorio.unb.br/handle/10482/54120-
dc.language.isoengpt_BR
dc.publisherElsevierpt_BR
dc.rightsAcesso Restritopt_BR
dc.titleSalivary flow and aging : a cross-sectional estimate of the annual decline per year of agept_BR
dc.typeArtigopt_BR
dc.subject.keywordFluxo salivarpt_BR
dc.subject.keywordSalivapt_BR
dc.subject.keywordEnvelhecimentopt_BR
dc.subject.keywordHipossalivaçãopt_BR
dc.subject.keywordGlândulas salivarespt_BR
dc.rights.license2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.pt_BR
dc.identifier.doihttps://doi.org/10.1016/j.oooo.2025.08.008pt_BR
dc.relation.publisherversionhttps://www.sciencedirect.com/science/article/pii/S2212440325011642?via%3Dihubpt_BR
dc.description.abstract1Objective. Although reduced salivary flow is often linked to aging, the extent of this decline across different age groups remains unclear. This study investigated the relationship between salivary flow and age, accounting for type 2 diabetes (T2D), polypharmacy, and fiber intake, aiming to estimate an annual rate of decline. Study Design. Adults and elderly participants (mean age 54 § 11 years) were recruited for this cross-sectional study. Resting salivary flow (RSF), stimulated salivary flow (SSF), pH, buffering capacity, viscoelasticity, medication intake and, T2D diagnosis were the main variables analyzed. Participants were classified as having hyposalivation if RSF < 0.1 mL/min or SSF < 0.7 mL/min. Associations were tested using unadjusted and adjusted robust linear regression (P < .05). Results. Sialometry was completed for 166 individuals. Hyposalivation was identified in 31% by RSF and 89% by SSF. Among adults under 60 years(n = 118), 28 (24%) had RSF hyposalivation and 99 (85%) had SSF hyposalivation. Older participants had significantly lower RSF and SSF. Salivary flow was estimated to decrease by 0.005 mL/min per year of age, independent of T2D and medication use. Conclusion. Salivary flow is associated with age, independent of T2D and medication use. Although the decline appears predictable (0.005ml/min/year), its clinical relevance warrants further investigation through longitudinal studies.pt_BR
dc.contributor.affiliationUniversity of Brasilia, School of Health Sciences, Department of Dentistrypt_BR
dc.contributor.affiliationUniversity of Brasilia, School of Health Sciences, Department of Dentistrypt_BR
dc.contributor.affiliationUniversity of Brasilia, School of Health Sciences, Department of Dentistrypt_BR
dc.contributor.affiliationUniversity of Brasilia, School of Health Sciences, Department of Dentistrypt_BR
dc.contributor.affiliationUniversity of Brasilia, School of Health Sciences, Department of Dentistrypt_BR
dc.contributor.affiliationUniversity of Brasilia, School of Health Sciences, Department of Dentistrypt_BR
dc.contributor.affiliationUniversity of Brasilia, School of Health Sciences, Department of Dentistrypt_BR
dc.contributor.affiliationUniversity of Brasilia, School of Health Sciences, Department of Dentistrypt_BR
dc.contributor.affiliationUniversity of Brasilia, School of Health Sciences, Department of Dentistrypt_BR
dc.contributor.affiliationUniversity of Brasilia, School of Health Sciences, Department of Dentistrypt_BR
dc.contributor.affiliationUniversity of Brasilia, School of Health Sciences, Department of Dentistrypt_BR
dc.contributor.affiliationUniversity of Brasilia, School of Health Sciences, Department of Nurserypt_BR
dc.contributor.affiliationUT Health, Department of Periodontologypt_BR
dc.contributor.affiliationUniversity of Brasilia, School of Health Sciences, Department of Dentistrypt_BR
dc.contributor.affiliationUniversity of Brasilia, School of Health Sciences, Department of Dentistrypt_BR
dc.contributor.affiliationUniversity of Brasilia, School of Health Sciences, Department of Dentistrypt_BR
dc.description.unidadeFaculdade de Ciências da Saúde (FS)pt_BR
dc.description.unidadeDepartamento de Odontologia (FS ODT)pt_BR
dc.description.unidadeDepartamento de Enfermagem (FS ENF)pt_BR
dc.description.ppgPrograma de Pós-Graduação em Odontologiapt_BR
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