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dc.contributor.authorMarques, Rafaella Cristhina Rego-
dc.contributor.authorSilva, Joana Rodrigues da-
dc.contributor.authorAlves, Larisse Santos Mendonça-
dc.contributor.authorEndres, Bruna Leis-
dc.contributor.authorPereira-Neto, Pedro Chagas-
dc.contributor.authorReis, Letícia Gonçalves-
dc.contributor.authorMelo, Carlos Daniel Correa de Oliveira-
dc.contributor.authorLeite, Eduarda Carvalho-
dc.contributor.authorAlves, Luana Severo-
dc.contributor.authorTeixeira, Nailê Dame-
dc.date.accessioned2026-02-23T20:07:49Z-
dc.date.available2026-02-23T20:07:49Z-
dc.date.issued2025-11-
dc.identifier.citationMARQUES, Rafaella Cristhina Rego, et al. Salivary parameters and dental caries in normoglycemic and hyperglycemic adults: findings from a cross-sectional analysis. Clin. Oral Invest., [S. l.], v. 29, 577, 2025. Disponível em: https://link.springer.com/article/10.1007/s00784-025-06666-x. Acesso em: 23 fev. 2026.pt_BR
dc.identifier.urihttp://repositorio.unb.br/handle/10482/54092-
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) e Empresa Brasileira de Serviços Hospitalares (Ebserh).pt_BR
dc.language.isoengpt_BR
dc.publisherSpringer Naturept_BR
dc.rightsAcesso Restritopt_BR
dc.titleSalivary parameters and dental caries in normoglycemic and hyperglycemic adults : findings from a cross-sectional analysispt_BR
dc.typeArtigopt_BR
dc.subject.keywordSalivapt_BR
dc.subject.keywordHiperglicemiapt_BR
dc.subject.keywordCárie dentáriapt_BR
dc.subject.keywordCárie radicularpt_BR
dc.subject.keywordDiabetes mellitus tipo 2pt_BR
dc.rights.licenseSpringer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.pt_BR
dc.identifier.doihttps://doi.org/10.1007/s00784-025-06666-xpt_BR
dc.relation.publisherversionhttps://link.springer.com/article/10.1007/s00784-025-06666-xpt_BR
dc.description.abstract1Objectives To investigate the association between salivary parameters and the number of coronal and root caries lesions (caries extent), as well as to assess whether glycemic status is influencing this association. Materials and methods This cross-sectional study included dentate adults aged≥35 years. Sociodemographic, behavioral, general and oral health data were collected, as well as salivary parameters, such as flow, pH, buffering capacity, viscoelasticity, and concentration of calcium, glucose, phosphate, and urea. The outcomes were the number of coronal caries (total, active, cavitated) and root caries (total, active, root caries index). Unadjusted and adjusted Poisson regression models were applied to estimate rate ratio (RR) and 95% confidence intervals (CI). Results The average of coronal caries extent was significantly higher in individuals with hyperglycemia. Phosphate stood out as a factor associated with coronal caries, both active lesions and cavitated lesions. Buffering capacity was also associated with coronal cavitated caries lesion. Regarding root caries, pH and calcium were associated with the total number of root lesions while pH and urea were associated with the number of active root lesions. Glucose levels and viscoelasticity were also associated with root caries. Conclusions Qualitative salivary parameters were associated with the number of caries lesions differently for coronal and root caries, even after adjusting for the glycemic status. Clinical relevance Association between caries and hyperglycemia should consider salivary parameters beyond flow, along with both caries lesion extent and activity outcomes.pt_BR
dc.contributor.affiliationUniversity of Brasilia, School of Health Sciencespt_BR
dc.contributor.affiliationUniversity of Brasilia, School of Health Sciencespt_BR
dc.contributor.affiliationUniversity of Brasilia, School of Health Sciencespt_BR
dc.contributor.affiliationUniversity of Brasilia, School of Health Sciencespt_BR
dc.contributor.affiliationUniversity of Brasilia, School of Health Sciencespt_BR
dc.contributor.affiliationUniversity of Brasilia, School of Health Sciencespt_BR
dc.contributor.affiliationUniversity of Brasilia, School of Health Sciencespt_BR
dc.contributor.affiliationFederal University of Santa Maria, School of Dentistrypt_BR
dc.contributor.affiliationUniversity of Brasilia, School of Health Sciencespt_BR
dc.description.unidadeFaculdade de Ciências da Saúde (FS)pt_BR
dc.description.unidadeDepartamento de Odontologia (FS ODT)pt_BR
dc.description.ppgPrograma de Pós-Graduação em Odontologiapt_BR
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