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dc.contributor.authorAlecrim, Hugo Muscellipt_BR
dc.contributor.authorDuarte, Sérgio Andurte Carvalhopt_BR
dc.contributor.authorAmaral, Maria Eduarda Bonavidespt_BR
dc.contributor.authorDiógenis, Filipept_BR
dc.contributor.authorCarneiro, Fabiana Piranipt_BR
dc.contributor.authorSousa, João Batista dept_BR
dc.date.accessioned2017-12-07T05:12:00Z-
dc.date.available2017-12-07T05:12:00Z-
dc.date.issued2015-01pt_BR
dc.identifier.citationALECRIM, Hugo Muscelli et al. Effect of glutamine supplementation on left colon healing in rats with extrahepatic biliary obstruction. Acta Cirurgica Brasileira, São Paulo, v. 30, n. 1, p. 73-79, jan. 2015. Disponível em: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502015000100073&lng=en&nrm=iso>. Acesso em: 17 abr. 2018. doi: http://dx.doi.org/10.1590/S0102-86502015001000010.pt_BR
dc.identifier.urihttp://repositorio.unb.br/handle/10482/29648-
dc.language.isoenpt_BR
dc.publisherSociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgiapt_BR
dc.rightsAcesso Abertopt_BR
dc.titleEffect of glutamine supplementation on left colon healing in rats with extrahepatic biliary obstructionpt_BR
dc.typeArtigopt_BR
dc.subject.keywordCólon (Anatomia)pt_BR
dc.subject.keywordCicatrização de feridaspt_BR
dc.subject.keywordCirurgiapt_BR
dc.subject.keywordRatospt_BR
dc.rights.licenseActa Cirurgica Brasileira - This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY NC 4.0). Fonte: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502015000100073&lng=en&nrm=iso. Acesso em: 17 abr. 2018.-
dc.identifier.doihttp://dx.doi.org/10.1590/S0102-86502015001000010pt_BR
dc.description.abstract1Purpose: to evaluate the influence of glutamine and obstructive jaundice on left colon healing in rats. Methods: sixteen male rats were allocated across four groups: LG - Common bile duct ligation followed by colotomy and bowel suture on postoperative day 7. Supplementation with glutamine 2% from day 4 after duct ligation until euthanasia. L - Common bile duct ligation followed by colotomy and bowel suture on postoperative day 7. No glutamine supplementation. M - Common bile duct manipulation followed by colotomy and bowel suture on postoperative day 7. No glutamine supplementation. MG - Common bile duct manipulation followed by colotomy and bowel suture on postoperative day 7. Supplementation with glutamine 2% from day 4 after duct manipulation until euthanasia. On the day of euthanasia, bursting pressure of the sutured bowel segment was measured and samples were collected for histopathological analysis. Results: there were no differences in bursting pressure among groups : LG vs. M (110 ± 28 vs. 173 ± 12; p = 0.08). Groups L and MG were not different from group M (156 ± 12 and 118 ± 22. Glutamine supplementation was associated with less edema, polymorphonuclear lymphocyte infiltration, bacterial colonies, and abscess formation, as well as with increased collagen formation. Conclusion: obstructive jaundice had no negative effect and glutamine supplementation had no positive effect on colonic scar strength in rats.-
dc.description.unidadeFaculdade de Medicina (FM)-
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